早期乳腺癌Mammotome活检术后原发灶切缘状况研究
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何劲松 E-mail:hjssums@sohu.com

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深圳市科技计划重点项目(200801004)。


Margin status after Mammotome biopsy for early-stage breast cancer
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    摘要:

    目的:探讨早期乳腺癌mammotome微创切除活检后切缘癌残留状况。
    方法:在高频超声引导下对283例临床不可触及的乳腺病灶施行mammotome微创切除活检术;对其中病理确诊为乳腺癌的52例施行保乳手术,术中对原发病灶切缘进行病理检查。
    结果:52例乳腺癌患者中,38例为乳腺导管内癌,14例浸润性导管癌;mammotome活检术后,43例原发灶切缘阴性,9例阳性。9例切缘阳性再行局部切除后5例切缘阴性,余4例切缘阳性改行乳房单纯切除。该4例术后病理为广泛性导管内癌(extensive intraductual component, EIC)。48例mammotome 活检与术后病理一致。
    结论:高频超声引导下mammotome微创活检诊断早期乳腺癌安全、可靠,对于局限的临床不可触及的乳腺癌病灶,可以收到病灶切除的效果。

    Abstract:

    Objective:To evaluate the cancer-residual status in the margins following Mammotome biopsy for early-stage breast cancer.
    Methods:A total of 283 patients with nonpalpable breast lesions underwent high-frequency ultrasound-guided mammotome biopsy. Among them, the margins status of patients with breast cancer finally diagnosed by mammotome biopsy was evaluated.
    Results:In total, 52 breast cancer patients were diagnosed by mammotome biopsy,   included 38 cases of ductal carcinoma in situ(DCIS) and 14 cases of invasive ductal carcinoma. There were 43 cases of negative margins and 9 cases of positive margins.The 9 cases with positive margins underwent lumpectomy for residual carcinoma. Of these 9 cases, 5 cases had negative margins and 4 cases had positive margins after lumpectomy, and the latter 4 cases with positive margins underwent simple mastectomy with a diagnosis of extensive intraductal component(EIC). The diagnosis by Mammotome biopsy was consistent with biopsy in 48 cases.
    Conclusions:High-frequency ultrasound-guided Mammotome biopsy is a safe and effective method to diagnose early-stage breast cancer of nonpalpable breast lesions, and could effectively excise the lesions.  

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何劲松| 王先明| 陈伟财| 王敏| 刘跃华| 陈训徹| 张家庭| 李征毅| 刘伟宗| 关弘.早期乳腺癌Mammotome活检术后原发灶切缘状况研究[J].中国普通外科杂志,2010,19(11):1192-1195.
DOI:10.7659/j. issn.1005-6947.2010.11.008

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  • 收稿日期:2010-03-11
  • 最后修改日期:2010-10-06
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  • 在线发布日期: 2010-11-15