Objective: To evaluate the effects of surgical treatment of acute deep vein thrombosis (DVT) of lower extremity. Methods : Thirtysix patients with acute DVT of lower extremity were treated by thrombectomy with thrombolytic,anticoagulant and compression on the affected lower extremity during and after operation. Results :No death and serious complications happened in this series. Thirtyone patients were followedup for 2 to 20 months with an average of 9 months. Symptoms disappeared totally in 23 patients, 8 patients had slight edema in the lower extremities. Conclusions :Combination of thrombectomy the thrombolytic and anticoagulant agent,and compression of the affected lower extremity is a safe and effective method in the treatment of acute DVT of lower extremity.