Objective:To study the prevalence of cholelithiasis among spinal cord injured （SCI）male patients, and the correlation of cholelithiasis with the SCI patients′ age, weight,and the level of injury, severity and duration of the SCI. Methods:One hundred male SCI patients including 58 patients with ASIA class A and B and 42 with ASIA class C and D,with aged 20-65 years old(average 46.5 years) were followed up.They suffered from a spinal cord injury more than one year. The control group consisted of 100 male volunteers without both SCI and biliary diseases, with aged 20-68 year old(average 42.6 years). All patients in the two groups underwent ultrasonographic imaging to evaluate the gallbladder and the biliary tract. Results:The prevalence of cholelithiasis was 26.0%
in the SCI group patients and 10.0% in the control group,the difference was statistical difference (P<0.01). But the the incidence of cholelithasis was not significant difference between the patients′ age ， weight ,SCI level, duration and severity（P>0.05）. Conclusions:SCI represents a major risk factor for the development of cholelithiasis . There are no correlation of cholelithiasis with the SCI patients′ age , weight,SCI level,severity and duration of SCI.