Objective:
To study the relevant factors of malignant change of colorectal adenoma. Methods: The clinical data of 276 cases of colorectal adenoma admitted in our hospital in recent 14 years were analyzed retrospectively . Results: Malignant change rate of the adenoma in the left colon was significantly higher than that in right colon(P<0.05);in the diameter of adenoma more than 2 cm was significantly higer than that in less than 1 cm( P<0.01);in villous adenoma was significantly higher than that in tubiform adenoma and mixed adenoma(P<0.01);in severe atypical hyperplastic adenoma was significantly higher than that in mild and moderate atypical hyperplatic adenoma(P<0.01);in multiple adenoma was significantly higher than that in single adenoma(P<0.05);in erosion and sessile adenoma were significantly higher than that in smooth and pedicle adenoma (P<0.01).Conclusions: The histological type, degree of atypical hyperplasia, the size, number, location of the adenoma and the patients age are the relevant risk factors of malignant chang factors of colonic adenoma.