Abstract:Objective:To summarize the experiences and lessons drawn from iatrogenic bile duct injury. Methods:The clinical records of 52 patients with iatrogenic bile duct injuries were studied retrospectively. Results:The injuries of 48 cases were resulted from extrahepatic bile duct operation,2 cases from partial gastrectomy and 2 cases from hepatectomy.The locations of injuries were at the juncture of common hepatic duct and common bile duct in 34 cases, the common hepatic duct in 6 cases,the common bile duct in 6 cases,the juncture of left and right hepatic duct in 4 cases，and the left and right hepatic duct each in 1 case respectively.Complete bile duct injuries were seen in 30 cases,and partial injuries in 22 cases .All patients were treated by operation. 8 cases were immediately discovered at the time of the initial operation and direct repair or end-to-end anastomosis with T-tube stent was done in 5 of the cases,direct insertion of T-tube drain in 1 case and Roux-en-Y hepaticojejunostomy in 1 case, all with good results;and in the another, a choledo choduodenostomy was performed,but re-operation by Roux-en-Y hepaticojejunostomy was done 3 years later,due to stricture of the anastomosis.For the 44 cases in which the bile duct injury was detected after the initial operation,Roux-en-Y hepaticojunostomy was done in 31 cases,hepaticoduodenostomy in 8 cases,drainage of common bile duct in 2 cases,plastic repair of common bile duct defect with jejunal flap in 1 case,hepaticojejunostomy(Longmire) in 1 case,and removal of stitches between the anterior and posterior wall of the common bile duct in 1 case.In the whole series,4 patients died,and 41 of 48 surviving patients were followed up.The excellent result rate was 82.9%,and 7 cases with poor results were cured by reoperation with Roux-en-Y cholangiojejunal anastomosis 2 months to 5 years after operation.Conclusions:The key to improvenment of treatment results of iatrogenic bile duct injury is awareness of its acurrence,early diagnosis, and eraly repair of the bile duct.The method of surgical therapy depends on the location and type of injury,and the time of detection after the injury.Roux-en-Y cholangiojejunal anastomosis gives the best results.