Abstract:Objective:To evaluate the method and outcome of surgical treatment for refractory slow-transit constipation (STC). Methods:Clinicopathologic data of 24 patients with severe STC which underwent colectomy in recent years were retrospectively analyzed. Results:18 of the patients underwent pancolectomy,and 6 underwent subtotal colectomy. All of the 14 STC patients complicated with outlet obstructive constipation(OOC) were corrected preoperatively by related surgery. The curative rate of surgical treatment was 95.8％,with an average of（3±1.9） times of bowel motion per day. The incidence of abdominal distention decreased from 75％ to 12.5％. One patient who underwent ileorectal anastomosis developed recurrent constipation. Conclusions:Colectomy produces satisfactory results in the majority of patients with refractory slow-transit constipation.Patients complicated with OOC should undergo energetic preoperative correction therapy,in order to ensure a satisfactory surgical outcome.