Objective:To study the causes of thyroid reoperation and the prevention of operative complications. Methods:The clinical data of 96 cases who underwent reoperation of thyroid were retrospctively analysed. Results:There were 31 cases of thyroid carcinoma(14.0%, P<0.05) undergoing reoperation, which was higer than that of total thyoid reoperation. There were 14 cases suffered postoperative complications in this series(14.6%), which was higher than for the patients undergoing primary operationrate(5.3%)(P<0.05). 11 of 51 patients who underwent two operative interventions on the same side thyroid suffered postoperative complications(21.6%), the rate was higher than for patients in whom both operations involved different sides(6.7%)(P<0.05). The interval between the two operations did not affect the rete of postoperative complications(P>0.05). Conclusions:Thyroid reoperation is more difficult than primary operation, and has a higher postoperative complications rate. Thyroid reoperation should be avoided or decreased, so the operator should do the best at the time of the primary operation, and timely reoperation should be performed when necessary. Thyroid reoperation should be performed carefully to decrease complications as much as possible.