Abstract:Objective:To evaluate the results of breast conservation surgery combined with radiotherapy for early stage breast cancer.Methods:The cinical data of 76 breast cancer patients who underwent breast conservation operation plus radiotherapy at Changzheng Hospital in the recent 6 years were retrospectively analyzed.Results:The 3-,and 5-year survival rate was 96.05% and 94.8%,respectively,the 3-,and 5-year local recurrence rate was 5.3% and 6.6% respectively, and the 3-,and 5-year breast conservation rate was 96.05% and 93.3%,respectively.Only one case had chest wall recurrence and there was no mortality.The case with recurrence was a 25-year old unmarried woman, who had an intense desire for breast conservation.After tumor recurrence,mastectomy was performed again and chemotherapy was administered.The patient is presently alive and in good health.Postoperative cosmetic physical results were satisfactory in 80.5% of cases.Conclusions:Breast conservation surgery plus radiotherapy can get satisfactory results.The important aspects for success of breast conservation treatment are standardization of resection and postoperative radiotherapy and integrated systemic therapy.