Abstract:Objective:To investigate the techniques of establishment of a model of combined liver-kidney transplantation in rats.
Methods :Healthy male SD rats were used as donors and recipients. The donor liver and kidney were resected simultaneously. The donor′s liver was transplanted on the basis of Kamada′s cuff technique. The donor′s renal artery and ureter were respectively anastomosed end-to-end to the recipient′s right renal artery and right ureter.
Results:60 cases of combined liver-kidney transplantation in rats were performed, among which 50 cases were successful. The successful rate was 83.3%.
Conclusions:This model of combined liver-kidney transplantation in rats can increase the success rate of operation, shorten the operation time and decrease the rate of postoperative complications. It is convenient, stable and reliable.