Abstract:Objective:To analyze the independent factors affecting the prognosis of gastrointestinal stromal tumor (GIST) patients undergoing radical operation.
Methods :The clinical characteristics and follow up data of the 97 patients with GIST underwent radical opsration from January, 2001 to January, 2003 in our hospital were retrospectively analyzed by univariate and multivariate methods.
Results: In the univariate analysis of the 97 cases, gender, tumor location, tumor size, tumor cell type, necrosis, mitotic count, and Gleevec administration postoperatively were found to be related to the prognosis of GIST. Multivariate Cox model analysis showed that tumor location, tumor size, tumor cell type, necrosis, mitotic count, and Gleevec administration postoperatively were independent prognostic factors for patients with GIST.
Conclusions:Tumor location, tumor size, tumor cell type, necrosis, mitotic count are important prognostic factors for patients with GIST undergoing radical operation.