Objective:To evaluate the clinical application of video assisted endoscopic thyroidectomy by transsubclavian approach.Methods :Sixtwo patients with thyroid adenoma, goiter or hyperthyroidism received thyroidectomy with endoscopic instruments through transsubclavian approach from December 2007 to July 2008. The age of the patients was from 12 to 65 years (mean 34 years).Results:All 62 cases had successful operation with no conversion.There were no severe surgical complications such as nerve damage or hemorrhage. Average operation duration was (120±32) min for the first 25 cases and (50±13.3)min for the later 37 cases. The stay time of hospitalization after operation was (4±0.5) days.Conclusions:The endoscopic thyroidectomy has the advantages of no neck scar, faster recovery and satisfactory cosmetic effect, and the technique is easy to learn.