Objective:To investigate the efficacy of miniincision thyroidectomy using LigaSure.Methods :Miniincision thyroidectomy with LigaSure was performed in 58 cases with thyroid diseases from Jan, 2006 to Dec, 2007.Results:The mean operation time was 45 (35-70 )min.The mean blood loss was 15(5-30)mL．The average drainage during 24 hours after operation was 20(10-30)mL. No hoarseness or hypocalcemia ocurred after operation．The average hospital stay was 3 (2-4)days.Conclusions: Using LigaSure for thyroidectomy can reduce the volume of bleeding, decrease complications rate， operation time and recovery time，and provides less trauma and a good cosmetic outcome.