Abstract:Objective:To explore the clinico-pathological characteristics of primary breast lymphoma(PBL).
Methods :The clinical data of 36 cases of PBL were analyzed retrospectively.
Results:Among the 36 cases of PBL，16 patients presented with stage Ⅰa disease, 14 patients with stage IIa disease,2 patients with stageⅡb disease, and 4 patients with stage Ⅳ. All of the patients underwent surgery and chemotherapy, and 20 cases had radiotherapy.
Thirty three patients (91.7%) were followed up for 3-193 months, during which time, 12 patients died, including 2 patients died of brain metastases，five patients died of bone metastasis，and five patients died of diffuse hepatic and pulmonary metastasis. In the 21 surviving patients, the survival time was 3～192 months, and the median survival time was 43.5 months.The overall 3-and 5-year survival rate was 70.1％ and 49.0％, respectively.
Conclusions:Most PBL are NHL.PBL is diagnosed basically by methods of pathology and immunohistochemistry，and operation combined with chemotherapy and/or radiotherapy is the best treatment method.