<FONT face=Verdana>Expression and significance of RANTES and its receptor in gastric cancer metastasis</FONT>

doi:10.7659/j.issn.1005-6947.2008.08.013

Home > Archive>Volume 17, Issue 8, 2008 >13-788. DOI:10.7659/j.issn.1005-6947.2008.08.013

Expression and significance of RANTES and its receptor in gastric cancer metastasis
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                        10.7659/j.issn.1005-6947.2008.08.013
                    
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Clc Number:R 735.2
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Abstract:

Abstract:Objective:To study the relation of RANTES and its receptor (CCR5) expression in gastric cancer and in lymph nodes with cancer metastasis.
Methods :The expression of CCR5 in gastric cancer and the expression of RANTES in lymph nodes were detected by the CCR5/DNA bivariate and RANTES/DNA bivariate by flow cytometry.
Results:The expression of CCR5 in gastric cancer and normal gastric tissue was (21.53±3.10)% and (10.10±1.30)% respectively（P＜0.05）; the positive rate of RANTES in lymph nodes with or without cancer metastasis was (63.50±5.25)% and (44.40±4.76)% respectively（P＜0.05）.
Conclusions:RANTES and its receptor might take part in modulation of gastric cancer metastasis.

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CAO Zhixin, XU Xiangshang, WANG Jing, LI Xiaolan, TAO Deding, GONG Jianping.Expression and significance of RANTES and its receptor in gastric cancer metastasis[J]. Chin J Gen Surg,2008,17(8):13-788.
DOI:10.7659/j. issn.1005-6947.2008.08.013

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Received:January 01,1900
Revised:January 01,1900
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Online: August 25,2008
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