Objective:To investigate the application and criteria of intraoperative parathyroid hormone assay during surgery of secondary hyperparathyroidism.
Methods :Subtotal parathyroidectomy was performed in 17 cases of secondary hyperparathyroidism. Parathyroid hormone assay was performed after induction of anaesthesia but before incision(PTH0) and 10min(PTH10) after subtotal parathyroidectomy. Two successive criteria of PTH decrease were used: (1) PTH10 of ≤150pg/mL; (2) PTH10 /PTH0≤30%.
Results:Fifteen cases met the criteria. There were PTH<15 pg/m in 4 cases, PTH of 15-65 pg/mL in 6 cases, and PTH of 65-185.2 pg/mL in 5 cases day 7 postoperatively. Bone pain resolved in all cases after operation.
Conclusions:Intraoperative parathyroid hormone assay can help for hyperparathyroid gland resection in secondary hyperparathyroidism, and can improve the successful rate of operation