Objective:To explore the production of medical polypropylene anti-bacterial mesh coated with triclosan，and study the properties of its controlled-release drugs, as well as the efficiency of the mesh coated with triclosan. Methods :A medical polypropylene anti-bacterial mesh coated with triclosan was produced by the method of solvent evaporation,with triclosan as antibacterial agent and ethylene-vinyl alcohol copolymer as carrier. The meshes were divided into four groups: A,B,C and D. The meshes in A,B and C (experimental) groups were coated with triclosan, and D group was control group. The ultrastructure of meshes of the 4 groups was observed under electron microscope.The slip diffusion method was used to observe the diameter of bacteriostasis-rings in different time periods. At the same time, we observed the maximum tensile strength of the mesh in transverse and longitudinal axis when they were pulled off before and after the experiment. Results:The surfaces of B group were uniform and smooth, and the coating could continuously release drugs during 7 days in sodium chloride. The diameter of bacteriostasis-rings in B group was significantly larger than that in control group (P<0.05) at 1d、3d、5d and 7d,but the maximum tensile strength of the meshes in transverse and longitudinal axis was not sigmificantly changed in the two groups. Conclusions:The medical polypropylene anti-bacterial mesh coated with triclosan by the method of solvent evaporation has the properties of controlled-release drugs and obvious anti-bacterial function. The biomechanics of the mesh remained the same essentially before and after the experiment. The study provides a new method and route for the clinical management of prosthetic patch infection after tension-free hernia repair.