Objective:To explore the treatment of type 2 diabetes mellitus (T2DM) patients by modified laparoscopic Roux-en-Y gastric bypass.
Methods:The clinical records of 11 patients with T2DM who underwent modified laparoscopic Roux-en-Y gastric bypass were retrospectively analyzed. The clinical parameters such as oral glucose tolerance test (OGTT), C-peptide releasing test (CPRT) and insulin releasing test  (IRT) were evaluated pre-and postoperatively.
Results:At one mnth after operation, there were no significant changes in BMI (P>0.05), but glycosylated hemoglobin，OGTT, CPRT and IRT were significantly ameliorated (P<0.05), and the diabetic symptoms were markedly relieved. Among them, 2 patients were followed up for more than 9 months, and 3 patients for more than 3 months.In these patients, there were no significant changes in BMI, but glycosylated hemoglobin，OGTT, CPRT and IRT were significantly ameliorated compared to before operation.
Conclusions:The modified laparoscopic Roux-en-Y gastric bypass is an effective treatment modality for non-and mild-obesity T2DM.