Objective:To investigate the effects of anticoagulant and thrombolytic treatment of deep venous thrombosis (DVT) of lower limbs on the prevalence of pulmonary embolism (PE).
Methods:The clinical records of 105 patients with DVT treated with anticoagulation and thrombolysis were reviewed and analyzed.The incidence of PE, the related risk factors including sex, age, the location and type of thrombosis was analysis to explore the relationship between them and the occurrence of PE.
Results:The incidence of PE in patients treated with anticoagulation and thrombolysis alone during hospitalization was 2.86% (3/105), while no patients suffered from PE after discharge from hospital. The occurrence of PE had no relationship with sex, age, or locations and types of thrombosis (P=0.086, 0.618, 1.0，1.0 respectively).
Conclusions:Strict adherence to the guidelines of anticoagulant and thrombolytic therapy can effectively reduce the incidence of PE in patients with DTV of lowe limbs. Thus, the indications for inferior vena cava filter placement should be strictly grasped by clinicians.