Objective:To summarize the main early complications after pancreatoduodenectomy and analysis of the probable causes.
Methods: The clinical data of 576 cases who underwent pancreatoduodenectomy (PD) in our department between Feb 1990 and May 2009 were analysed retrospectively.
Results:There were 92 early postoperative complications occurred in 85 patients（14.8%）. Gastrointestinal dysfunction, pancreatic leakage, intra-abdominal infections and hemorrhage were the most of complications, and 7 cases died during perioperative period(mortality 1.22%), among which 3 died of multiple system organ failure, 2 died of hemorrhagic shock and 2 died of toxic shock. Preoperative hypoproteinemia and hyperbilirubinemia complicated with a high incidence of postoperative complications on multivariate analysis.
Conclusions:Meticulous preoperative preparation,delicate intraoperative technigne and close postoperative observation are the key points to decrease early complications and improve the prognosis of the patients who undergo PD.