Objective: To explore the clinical efficacy of hepatic segmentectomy under segmental staining and intraoperative chemoembolization for primary liver cancer(PLC).
Methods: Twenty cases of liver cancer underwent hepatic segmentectomy under segmental staining and intraoperative chemoembolization (observed group), the results were compared with 22 cases of PLC after treated by routine hepatectomy(control group).AFP,CT and MRI were regularly used after hepatectomy to evaluate the outcome.
Results: In observed group, the operative blood loss was(295±105)mL，blood transfusion was(280±85)mL,  liver function levels were in  the normal range accounted for 15%(3/20) one week  postoperatively, the incidence of postoperative complications was 40% (8/20),the postoperative 3-year survival rate was 60%,and the postoperative local recurrence rate was 35%; while in the control group, these parameters were (490±140)mL, (370±105)mL,  40.9%(9/22), 45.5％（10/22）,  40.91% and 68.18% respectively. In observed group, the operative blood loss, blood transfusion, cases with liver function levels in the normal range, the incidence of postoperative complications, postoperative 3-year survival rate, and postoperative local recurrence rate were significantly lower than those in the control group(P<0.05). The postoperative 3-year survival rate in observed group was significantly higher than that in the control group (P<0.05)，but the incidence of postoperative complications in the two groups was not statistically different (P>0.05).
Conclusions: The hepatic segmentectomy under segmental staining and intraoperative chemoembolization for PLC may reduce postoperative complications，lower postoperative relapse rate and improve survival rate.