Objective: To investigate the value of laparoscopy combined with choledochoscopy in treatment of cholecystolithiasis complicated with choledocholithiasis.
 Methods: Clinical data of 168 patients with  cholecystolithiasis and choledocholithiasis treated in our haspital from June 2005 to June 2009 were analysed. Ninety patients were randomly selected and treated by laparoscopic cholecystectomy combined with choledocholithotomy and T-tube drainage (group A), the other 78 patients, as control group, underwent routine cholecystectomy and choledocholithotomy plus T-tube drainage by laparotomy (group B).
 Results: The hospital stay and the mean time to passage of flatus in group A was much shorter than that in group B (P<0.05); and the postoperative complication rate in group A was obviously lower than that in group B(P＜0.05); while  the mean operative time and cost of hospitalization between the two groups had no statistical difference（P>0.05）.
 Conclusions: Laparoscopic cholecystectomy combined with choledocholithotomy and T-tube drainage for cholecystolithiasis and choledocholithiasis is a microtrauma management with advantages of quick recovery and shorter hospital stay, that makes it superior to the open operation.