Objective: To evaluate therapeutic effects of hepatectomy for hepatolithiasis.
 Methods: Retrospective analysis of the clinical data，including stones distribution, operative modality, postoperative complications, and therapeutic effect of hepatectomy for hepatolithiasis in 107cases admitted  in our hospital from June 2000-July 2007 was undertaken.
 Results: Among the 107 patients, left lateral lobectomy was performed in 80 cases, left hepatectomy  in 14 cases,  right hepatectomy in one case and selective combined segmentectomy in 12 cases.The postoperative residual stone rate was 10.3% (11/107 cases), but the final residual stone rate was 3.7% (4 /107 cases) after stone extraction by subsequent T-tube route or endoscopic sphincterotomy (EST). Postoperative complication rate was 29.9%（32  /107 cases）, while in left lateral lobectomy, left hepatectomy, right hepatectomy and selective combined segmentectomy complications were 23.7% (19/80 cases), 42.8% (6/14 cases) and 53.8% (7/13 cases), respectively. The latter 2 procedures had a higher rate of complications than the former 2 procedures (P<0.05).
 Conclusions: Liver resection for intrahepatic bile duct stones has a relatively low rate of residual stones and stone recurrence, it is safe and effective.