Objective：To study the effect of extended Whipple′s resection for carcinoma of head of pancreas.
Methods：Seventy-five patients who underwent surgery for carcinoma of head of pancreas were divided into control group (traditional Whipple′s operation,n=38) and study group (extended Whipple′s operation, n=37). The survival, complication, mortality and recurrence rates were compared between the 2 groups.
Results：In control group and study group, the complication rate was 60.53%and 29.73%;  the  mortality rate was 5.26% and 2.70%; the recurrence rate was 78.95% and 35.14%; and 3-year survival rate was 15.79% and 35.14%, respectively.
Conclusions：Extended Whipple′s resection for carcinoma of head of pancreas can decrease postoperative recurrence rate and  increase 3-year survival rate.