Objective:To evaluate the clinical values of selective hemihepatic vascular occlusion in hepatectomy for large hepatocellular carcinomas.
Methods:Forty patients with large hepatocellular carcinomas who underwent hepatectomy with selective hepatic inflow and outflow occlusion of tumor-bearing liver were retrospectively analyzed.
Results:All the 40 patients underwent hepatectomy successfully. The blood losts during the operation was 100-800 mL (average 360 mL). The operation time was 90-150 min(average 116 min). Intraoperative blood transfusion was not performed in twenty-five patients. All patients recovered completely and were discharged without liver function failure or other severe complications. There was no perioperative death.
Conclusions:Selective  hemihepatic vascular occlusion in hepatectomy for large hepatocellular carcinomas is a safe and effective method with advantages of controlling hemorrhage,  decreasing liver damage and gut barrier injury, avoiding air embolism and preventing metastasis.