Objective：To analyze the related factors affecting the prognosis of gastric cancer patients undergoing operation.
Methods：The clinical characteristics and follow up data of 887 patients with gastric cancer treated from January 1990 to December 2001 in our hospital were retrospectively analyzed by univariate and multivariate methods.
Results：Of the 887 cases, the overall 1-, 3- and 5-year survival rate was 79.63%, 49.29% and 43.40%, respectively. In the univariate analysis, tumor location, TNM stage, pathological type, operative method, and chemotherapy were related to the prognosis of patients with gastric cancer. Multivariate Cox model analysis showed that TNM stage, pathological type, operative method, and  chemotherapy were the related factors for patients with gastric cancer.
Conclusions：TNM stage, pathological type, operative method, and  chemotherapy are important prognostic factors for patieuts with gastric cancer undergoing operation.