Objective：To investigate the diagnosis and treatment of thyroid cancer.
Methods：Retrospective analysis of the clinical data of 236 patients with  thyroid cancer who underwent surgical treatment in our hospital from 2002-2008 was conducted.
Results：Solid thyroid nodules or cystic-solid nodules were found in 225 patients (95.53%) by B-ultrasonography (BUS)  preoperatively, among them, micro-calcification  within nodules was found in 78 cases (33.05%).  B ultrasound-guided fine-needle aspiration biopsy was performed in 81 cases, and had positive rate of 87.65%. Intraoperative frozen section was examined in 221 cases, among which 208 cases of thyroid cancer were diagnosed, a positive rate of 94.11%. Postoperative pathological examination confirmed lymph node metastasis in 68 cases (28.81%). Partial thyridectomy was performed in 15 cases, ipsilateral lobectomy in 44 cases, and radical resection in 177 cases. In 25 cases who was misdiagnosed before operation, and correct diagnosis was comfiromed by pathological examination  after partial resection or ipsilateral lobectomy, then a secondary or more surgical procedures were performed, with residual cancer rate of 56.0% (14/25).
Conclusions：BUS finding of thyroid nodules containing micro-calcification has important significance  for thyroid cancer diagnosis, and in combination with B ultrasound-guided fine-needle aspiration biopsy could significantly improve the accuracy of preoperative diagnosis. Intraoperative frozen section diagnosis is an important method for confirmation of thyroid cancer. Ipsilateral total lobectomy+ isthmectomy+ contralateral subtotal lobectomy+ selective neck dissection is the main surgical method for thyroid cancer. For misdidanosed cases, a secondary operation should be performed as early as possible.