Characteristics and treatment of childhood thyroid carcinoma
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R 736.1

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    Abstract:

    Objective:To investigate the clinicopathologic characteristics and therapy of thyroid carcinoma in children.
    Methods:A retrospective review of the clinical data of 26 childhood patients with thyroid carcinoma treated in the Second Affiliated Hospital, Nanchang University from Jan 1990 to Dec 2005 was conducted.

    Results:There were 15 girls and 11 boys in this series. All cases were diagnosed by histological evaluation: papillary carcinoma was diagnosed in 14, follicular carcinoma in 9, papillary follicular carcinoma in 2 and medullary carcinoma in 1. Cervical lymph node metastasis was found in 21 patients (80.8%). Among them, 1 underwent tumor enucleation, 5 underwent unilateral lobectomy and unilateral central compartment lymph node clearance, 15 underwent unilateral lobectomy and unilateral neck dissection, and 5 underwent neartotal or total thyroidectomy and bilateral neck dissection. All patients were followed up with tumor-free survival in 24 cases. The 5- and 7-year survival rate was 96.2% and 91.6%, respectively.Three patients required intravenous calcium supplementation postoperatively, but there was not a single case of permanent hypoparathyriodism or recurrent nerve paralysis during follow-up.
    Conclusions:Almost thyroid carcinoma in children are differentiated carcinomas,  the prognosis is significantly better after surgical treatment.

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HUANG Liang, ZHOU Wei, YUAN Yunfei, TU Qunfei, ZHANG Kaihua, XIONG Jixin. Characteristics and treatment of childhood thyroid carcinoma[J]. Chin J Gen Surg,2010,19(11):1173-1176.
DOI:10.7659/j. issn.1005-6947.2010.11.002

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History
  • Received:May 17,2010
  • Revised:October 11,2010
  • Adopted:
  • Online: November 15,2010
  • Published: