Objective：To study the outcome of endovascular therapy alone or combined prosthetic bypass surgery for  arteriosclerosis obliterans of lower limbs.
Methods：The clinical data of 48 patients with arteriosclerosis obliterans, multiple levels of stenosis and postoperative arterial reocclusion were retrospectively andayzed.
Results：Endovascular therapy  alone was performed in 24 cases, including balloon dialation in 4 patients and plus stent in 20 patients; and combined with prosthetic bypass graft  in 24 patients.  In 48 patients,rest pain disappeared and the ulcers healed after the operation, and  ABI increased gradually after treatment(P＜0.01). Forty-six patients had regular follow-up for 3 months to 82 months, of whom 43 cases had no recurrence.
Conclusions：Endovascular therapy alone or combined with surgical treatment is a feasible,safe and effective choice for arteriosclerosis obliterans of lower limbs, and with a low complication rate and quick recovery.