Objective:To evaluate the influences on oxygen free radicals  of  SIRS due to abdominal infection treated by Salvia Miltiorrhiza  and Shengmai injection.
Methods:Fifty patients with SIRS due to abdominal infection were divided into 2 groups：Group A,  treated by  combined western medicine (n=25); Group B, treated by combined  western medicine plus Salvia Miltiorrhiza and  Shengmai injection (n=25). Plasma malondialdehyde(MDA) and Superoxide dismutase（SOD） were measured before treatment and on day  2 and day 4 after treatment.
Results:The serum levels of  MDA in group B decreased more rapidly than those in group A, and  the serum levels of  SOD  in group B increased more rapidly than those in group A.
Conclusions:On the basis of combined western medicine treatment, addition of Salvia Miltiorrhiza and Shengmai injection has therapeutic effect on SIRS by decreasing the harmful MDA factor and increasing the defensive SOD factors, and thereby can alleviate inflammatory injury and prevent further MODS.