Objective:To investigate the clinical value of laparoscopic gastric partial resection for gastric stromal tumors. Methods:The clinical data of 22 cases who underwent laparoscopic gastric partial resection for treatment of gastric stromal tumors from Apr 2009 to Oct 2010 in our hospital were analyzed restrospectively. Results:All cases were operated on successfully without conversion to open surgery. The biopsy of the edge of specimens were all tumor negative. The average operative time was 55min, the mean intra-operative blood loss was only 50-150 mL, gastrointestinal function resumed at 24-48h after surgery on average, the postoperative hospitalization was 3-7d, and no postoperative complications occurred. Conclusions:Laparoscopic partial gastric resection for gastric stromal tumors (1.5-3 cm diameter) is safe, and has the merits of little contamination, minimal invasion and rapid recovery.