Objective：To study the imaging and clinicopathological features, treatment, and prognosis of hepatic angiomyolipoma (HAML).
Methods：The clinicopathological data of 5 patients with HAML treated in our haspital from 2007 to 2009 were retrospectively analyzed. All patients underwent excision of hepatic mass or partial liver resection for hepatic parenchymal disease as suggested by B ultrasound, CT or MRI examination.
Results：The imageological examination showed that the masses exhibited regular shapes and clear margins. Microscopically, the tumors were composed of a mixture of blood vessels, smooth muscle and fat tissues in different proportions. Immunohistochemical staining showed that the tumors were positive for HMB45 and SMA. These tumors were finally comfirmed to be HAML by routine pathological and immunohistochemical diagnosis. No recurrence or death occurred during the half to 1 year periods of postoperative follow-up.
Conclusions：HAML is a rare tumor of liver and its biological behavior is generally benign. HAML is likely to be misdiagnosed as malignant tumor due to the diverse morphological traits. Pathologists must be aware of the histological findings of HAML to avoid misdiagnosis in their pathological evaluation.