Objective: To determine the efficacy of endovascular treatment of infrarenal abdominal aortic aneurysm (AAA) using domestic unibody bifurcated stent-graft. Methods: The clinical data of 27 patients with infrarenal AAA undergoing endovascular aneurysm repair (EVAR) using domestic unibody bifurcated stent-graft from September 2009 to June 2011 in our department were retrospectively analyzed. Results: Endovascular repair of AAA was successfully performed in all the 27 patients. CTA or DSA examination during the follow-up (2 to 20 months) after the operation revealed that the aneurysm body had been isolated completely, no stent displacement, distortion or endoleak occurred. Conclusions: Endovascular repair of infrarenal AAA using domestic unibody bifurcation stent-graft is safe and effective. It has the advantages of simple manipulation, low cost and less complications compared with the separated stent-graft.