Objective: To investigate the alteration and tendency of bodily pain (BP) in patients with lower extremity deep vein thrombosis (DVT) during a short-term observation following standard non-surgical treatment. Methods: The scores of BP dimension in SF-36 scale in 57 patients admitted from March 2009 to October 2011 and fulfilled the inclusion criteria were measured by questionnaire. Measurements were performed before and 1, 2, 3 and ≥4 (4–8) months after treatment, respectively. Information database of the patients was established by EPidata 3.1 software, and then their BP alterations as well as the influence exerted by wearing compression stockings during the short-term period after non-surgical treatment were analyzed using SPSS 12.0 statistical software. Results: Finally, 50 patients were eligible and entered the database. The distributions of age (P=0.997), nationality (P=0.477) and sex (P=0.989) of the patients at different observation time points with different number of enrolled cases were relatively even and comparable. BP dimension scores of the patients were significantly different before and after standard non-surgical treatment (P<0.001), but had no significant differences were found among the different observation time points after treatment in any pairwise comparison (all P>0.05). Whether wearing the compression stockings or not had no obvious influence on the alteration trend of BP dimension scores of the patients after treatment. Conclusion: After the non-surgical treatment, the BP of the DVT patients is improved and transits into a stable phase, on which the wearing of compression stockings seems to exert no impact.