Imaging examination techniques play very important roles in diagnosis of liver diseases, among which CT or MRI imaging has the most practical value, and has become a routine examination for diagnosis and differential diagnosis of liver diseases. The application value of MRI imaging becomes increasingly important in diagnosis of liver diseases, due to its excellent tissue discrimination and a variety of contrast agents for use. Here, the authors address the application of Primovist, a liver-specific contrast agent for MRI, in diagnosis of liver diseases.