Surgical diagnosis and treatment of primary hyperparathyroidism
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R653.3

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    Abstract:

    Objective: To investigate the surgical diagnosis and treatment of primary hyperparathyroidism (PHPT). Methods: The clinical data of 86 PHPT patients treated between 2002 and 2012 were retrospectively analyzed. Results: Of the patients, the initial symptoms presented in 45 cases as skeletal disorders, in 21 cases as urological problems, and in 14 cases as gastrointestinal upsets; six cases had no obvious symptoms. The mean calcium level was (3.13±0.46) mmol/L and the median parathyroid hormone (PTH) level was 864.6 pg/mL in patients before operation. The detection rate of diseases by ultrasound, 99mTc-MIBI, and CT was 90.3%, 95.0% and 78.6%, respectively. Unilateral neck exploration was performed in 58 patients with a solitary parathyroid adenoma (including 5 cases of ectopic parathyroid adenoma), and bilateral neck exploration was performed in 11 patients with multiple parathyroid adenomas, 15 patients with parathyroid adenoma combined with bilateral nodular goiter and 2 patients with parathyroid hyperplasia. Eighty cases were followed up for 3 months to six years, and all of them survived without recurrence. Conclusion: For PHPT, the calcium and PTH levels are the bases for qualitative diagnosis; ultrasound and 99mTc-MIBI are the main approachs for localization; surgery is the most effective treatment method and unilateral neck exploration is the common procedure.

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GAO Zhiqiang, SHEN Ming, YU Yahong, XUE Xinbo. Surgical diagnosis and treatment of primary hyperparathyroidism[J]. Chin J Gen Surg,2013,22(11):1446-1449.
DOI:10.7659/j. issn.1005-6947.2013.11.015

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History
  • Received:March 18,2013
  • Revised:October 09,2013
  • Adopted:
  • Online: November 15,2013
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