Breast cancer is a common malignant tumor in China. Its prevalence is increasing and the patients are getting younger, and thus it is a great threat to the health of women. With the rapid development of translational medicine, the concept of integrated therapy of breast cancer is gradually accepted by the public, among which, endocrine therapy has attracted enormous attention, due to its potent efficacy and low toxicity. In this paper, the authors overview the recent research progress in endocrine therapy of breast cancer involving ovarian function suppression, anti-estrogen drugs, progesterone, testosterone, aromatase inhibitors, luteinizing hormone and luteinizing hormone releasing hormone analogs and so on.