Objective: To investigate the options of treatment strategy for acute limb ischemia (ALI). Methods: The clinical data of 15 patients with ALI, treated from 2012 to 2013, were retrospectively analyzed. Results: All patients underwent evaluation of the severity of acute limb ischemia before treatment. Of the patients, 11 cases were caused by embolism and 4 cases were caused by thrombosis; 9 cases had an aortic or iliac artery occlusion, 3 cases had superficial femoral artery occlusion, and one case each had a lesion in the popliteal artery, artery of the lower leg and brachial artery, respectively; limb ischemia in one case was classified as grade IIa, 12 cases were grade IIb, and 2 cases were grade III. All the patients, except one who refused primary amputation and received drug treatment only, underwent urgent revascularization that included surgical embolectomy in 11 cases, endovascular thrombolysis in 2 cases, and hybrid procedure in one case. During their hospital stay, no death occurred, amputation was performed in 2 cases, reperfusion injury developed in 3 cases but fasciotomy was not required in any of them, and the median length of hospital stay was 9 (3–27) d. During a mean follow-up period of 9 (1–21) months, 3 patients (20%) died, and no additional amputation was performed. The total limb salvage rate was 66.7%. Conclusion: Accurate evaluation of severity of ischemia, and prompt and appropriate revascularization procedure are crucial for treatment of ALI.