The Notch pathway plays an important role in cancer occurrence, development, migration and metastasis as well as angiogenesis, and is also responsible for the maintenance of the properties of tumor stem cells, and regulating their tumorigenesis and differentiation. In this paper, the authors present the latest progress concerning Notch signaling pathway in cholangiocarcinoma.
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SU Jin, DENG Xiaofeng, LIU Bo, XIONG Li, WEN Yu, MIAO Xiongying. Notch signaling pathway in cholangiocarcinoma: recent progress[J]. Chin J Gen Surg,2015,24(8):1175-1180. DOI:10.3978/j. issn.1005-6947.2015.08.024