Objective: To investigate the clinical characteristics and treatment measures of post-thyroidectomy hemorrhage. Methods: The clinical data of 3 417 patients undergoing thyroid surgery between April 2014 and May 2015 in the First Affiliated Hospital of Zhengzhou University were reviewed, from which 8 cases developing postoperative hemorrhage were picked up and analyzed. Results: The 8 patients included 2 cases of subcutaneous hematoma, 2 cases of anterior jugular vein hemorrhage, 2 cases of superior thyroid artery hemorrhage, one case of inferior thyroid artery hemorrhage, and one case of hemorrhage of the anterior muscles of the neck. All the 8 patients underwent corresponding management with no serious consequences, such as asphyxia, occurring in any of them, and they were discharged with grade-1 wound healing. Conclusion: Early detection and aggressive treatment are crucial for reducing the complications of post-thyroidectomy bleeding, and the traditional ligation or suture with silk thread should not be overlooked.