Objective: To investigate the clinical efficacy of percutaneous interventional treatment for complex aortoiliac arterial occlusion. Methods: The clinical data of 16 patients with complex aortoiliac arterial occlusion were retrospectively analyzed. All patients underwent interventional procedures by using subintimal recanalization technique and catheter-capture technique to establish a working guidewire channel via multi-puncture approach, and then underwent balloon dilatation and kissing stent placement. Results: Operation was performed successfully in all the 16 patients with complex aortoiliac arterial occlusion, and the surgical success rate was 100%. Among them, blood flow was completely restored and symptoms were improved significantly in 15 cases, and symptoms were moderately improved in 1 case, in whom the symptoms of lower limb ischemia disappeared. Puncture-site hematoma occurred in one case, and the incidence of postoperative complications was 6.25%. All patients were followed up for 3 to 48 months. Intra-stent stenosis or thrombosis occurred in 5 cases, and blood flow was restored after a second endovascular intervention. The 12-, 24- and 36-month patency rate was 87.5%, 81.25% and 68.75% respectively. Conclusion: For complex aortoiliac arterial occlusion, percutaneous interventional treatment can rapidly recanalize the occlusion and restore the blood flow with low incidence of complications, so it has satisfactory clinical efficacy.