Abstract:Objective:To evaluate the value of breast fiberoptic ductoscopy（FDS）in diagnosis and treatment of intraductal lesions.
Methods :The clinical data of 548 patients with nipple discharge who underwent FDS from Sep 2004 to Nov 2006 were retrospectively analyzed.
Results:Of 548 patients with nipple discharge, the FDS diagnosis was galactophoritis in 59 cases, ductal ectasia in 117 cases, ductal ectasia coexistent with galactophoritis in 185 cases, intraductal papilloma in 159 cases, intraductal papillomatosis in 12 cases and breast carcinoma in 16 cases.One hundred and thirty-five cases had surgical therapy in our hospital,among them,91 cases had tumor resection or segmentectomy under localization by FDS, and 44 cases had segmentectomy after breast duct infusion with methylene blue. The diagnostic conformity rate of FDS localization group（97.8%）was significantly higher than that of breast duct infusion of methylene blue group（86.4%）(P<0.01).
Conclusions:FDS is not only a reliable method of diagnosis for patients with breast intraductal lesion, but can assist in localization and in operative removal of breast intraductal neoplasm. The localization by FDS can avoid blindness of operation and help to improve the detection of intraductal lesions.