Surgical versus conservative treatment for small-diameter abdominal aortic aneurysm: a meta-analysis
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R654.3

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    Abstract:

    Objective: To systematically evaluate the efficacy of surgical and conservative treatment for small-diameter abdominal aortic aneurysm (AAA). Methods: The randomized controlled trails (RCTs) comparing surgical (endovascular aortic repair and open surgery) and conservative treatment for small-diameter AAA were collected by searching the national and international databases. After assessment of methodological quality of the included studies according to the Cochrane Reviewers’ Handbook criteria, Meta-analysis was performed by using RevMan 5.1 software. Results: Four RCTs were finally included, with a total of 3 314 patients, of whom 1 680 cases underwent surgical treatment and 1 634 cases underwent conservative treatment. Results of Meta-analyses showed no significance difference between the two groups of patients in all-cause mortality (SMD=0.97, 95% CI=0.68–1.38), aneurysm-related mortality (SMD=0.81, 95% CI=0.56–1.17), incidence of aneurysm rupture (SMD=0.49, 95% CI=0.09–2.54) and mortality within postoperative 30 d or during hospitalization (SMD=0.88, 95% CI=0.60–1.29) (all P>0.05). Conclusion: In treatment of small-diameter AAA, the outcomes between surgery and conservative treatment are similar. However, the clinical significance of this conclusion is uncertain, and the authors based on comprehensive analysis deem that small-diameter AAA still needs aggressive surgical treatment.

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ZHANG Xianlan, GUO Jiangang. Surgical versus conservative treatment for small-diameter abdominal aortic aneurysm: a meta-analysis[J]. Chin J Gen Surg,2015,24(6):792-799.
DOI:10.3978/j. issn.1005-6947.2015.06.005

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History
  • Received:February 14,2015
  • Revised:May 18,2015
  • Adopted:
  • Online: June 15,2015
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