Influence of renal capsule block on gastric myoelectrical activity and motility in rats
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R614.4

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    Abstract:

    Objective: To investigate the influence of renal capsule block on gastric myoelectrical activity and motility in rats, and provide a theoretical basis for using this method in treatment of gastrointestinal motor disorders. Methods: Thirty-six SD rats were equally randomized into 3 groups, and then underwent intraperitoneal injection of atropine, neostigmine or normal saline to create the models of gastrointestinal motor suppression (suppression group), gastrointestinal hyperactivity (hyperactivity group), or normal control (control group), respectively. Rats in each group underwent renal capsule block procedure by renal capsule injection of lidocaine. The gastric electrical activity and gastric residual rate in rats of each group were detected and compared. Results: Compared with control group after model creation, the average peak amplitude and cycle length of the electrogastrography were reduced, and gastric residual rate was increased significantly in suppression group, while the changes in these parameters in hyperactivity group were opposite to those in hyperactivity group (all P<0.05). After renal capsule block, all the parameters in control group showed no significant change compared with those before renal capsule block (all P>0.05), while the average peak amplitude and cycle length of the electrogastrography in suppression group were elevated and gastric residual rate was decreased significantly compared with the values before renal capsule block, and the average peak amplitude and cycle length of the electrogastrography in hyperactivity group were decreased and gastric residual rate was increased significantly compared with those before renal capsule block (all P<0.05). Conclusion: Renal capsule block exerts no obvious impact on normal gastric myoelectrical activity and motility, but has a bidirectional correction effect on abnormal gastric myoelectrical activity and motility.

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TANG Yongzhong, LIAO Qin, LU Xi. Influence of renal capsule block on gastric myoelectrical activity and motility in rats[J]. Chin J Gen Surg,2015,24(6):834-837.
DOI:10.3978/j. issn.1005-6947.2015.06.013

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History
  • Received:November 11,2014
  • Revised:April 25,2015
  • Adopted:
  • Online: June 15,2015
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