Liver resection is an important treatment modality for liver diseases. However, the postoperative complications adversely affect the outcome of treatment. Systemic inflammatory response after liver resection is a crucial factor for causing postoperative complications. Inhibiting the inflammatory reaction can effectively reduce the incidence of postoperative complications, which has an important clinical significance in postoperative recovery of patients. In recent years, precise hepatectomy technique has received increasing attention in terms of relieving postoperative inflammation. Here the authors, based on the relevant literature review, summarize the alleviating effect of precise hepatectomy on postoperative inflammation.