Objective: To investigate the safety and efficacy of laparoscopic inguinal hernia repair with utilization of the enhanced recovery after surgery (ERAS) protocols. Methods: The clinical data of 360 patients undergoing laparoscopic inguinal hernia repair with standard ERAS protocols between July 2013 and September 2016 in Department of General Surgery of Xiangya Hospital were retrospectively analyzed. Results: The median operative time for the entire group was 68 (30 to130) min, for unilateral inguinal hernia was 48 min and for bilateral inguinal hernia was 91 min. The incidence of postoperative complications was 8.9% (32/360), which mainly included urinary retention in 15 cases (4.2%) and seroma in 25 cases (6.9%). No wound infection or perioperative death occurred. The median length of postoperative hospital stay was 1 d. The pain score measured by numeric rating scale (NRS) on the first postoperative day was 1.8±1.2, and the NRS score in the patients under 65 years of age was significantly higher than in those over 65 years of age (P=0.01). The score of Inguinal Pain Questionnaire (IPQ) was 1.6 (0 to 8) at one month postoperatively. Conclusion: Laparoscopic inguinal hernia repair with utilization of ERAS protocols is safe and effective, with low incidence of postoperative complications and high patient satisfaction.