Objective: To introduce a novel method for liver parenchymal transaction, i.e., the snip-electrocoagulation technique. Methods: The clinical data of 30 consecutive patients undergoing liver resection for liver tumor in the Department of General Surgery of Xiangya Hospital, Central South University from June 2015 to February 2016 were reviewed. All patients received snip-electrocoagulation technique, namely using dissecting scissors and bipolar coagulation scalpel only, for parenchymal transection during operation. The perioperative data and the technical essentials of this method were analyzed. Results: Of the 30 patients, there were 24 cases of hepatocellular carcinoma with cirrhosis; the procedures included one segment resection in 10 cases, two segments resection in 12 cases and hemihepatectomy in 8 cases. The mean transection time, operative time, total blood loss and length of hospital stay was 19.8 (12–38) min, 129.3 (80–180) min, 207.5 (60–600) mL and 7.1 (5–14) d, respectively, and none of the patients required blood transfusion. Among 4 patients (13.3%), a total of 6 postoperative complications occurred, including pleural effusion and ascites in 4 cases, and pneumonia and bile leak in one case each, but all of them were managed successfully by conservative treatment. There was no rebleeding or death within postoperative one month. Conclusion: Snip-electrocoagulation technique is safe and effective for parenchymal transection, and it is recommended as an alternative method for parenchymal transection to be used in clinical practice.