Abstract:Objective: To investigate the relations of blood glucose and lipid as well as other factors with the intraluminal thrombus (ILT) in abdominal aortic aneurysm (AAA) patients.
Methods: The clinical data of 151 AAA patients treated in the Department of Vascular Surgery of the First Affiliated Hospital of China Medical University from July 2014 to October 2017 were analyzed retrospectively. The factors associated with ILT in AAA were determined by using statistical methods.
Results: Of the 151 patients, 132 cases were found having ILT and 19 cases without ILT. In patients with ILT compared with those without ILT, the proportions of male cases and cases with peripheral artery disease were elevated, and the levels of triglyceride (TG), creatinine (Cr) and D-dimer (D-D) were increased (all P<0.05). As for the ILT thickness, the ILT thickness in male patients was greater than that in female patients, and patients with diabetes mellitus (DM) was less than that in patients without DM (both P<0.05); the results of grouped comparison according to the ILT thickness showed that the aneurysm diameter of AAA was smaller, the proportion of DM cases and the fasting blood-glucose (FBG) level were higher, the levels of total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and D-D were lower in thin ILT group than those in thick ILT group (all P<0.05). Correlation analysis shows that the ILT thickness were positively correlated with TC (r=0.206, P=0.018) and LDL-C (r=0.227, P=0.009).
Conclusion: Blood lipid is an important factor for the occurrence and development of ILT, while the impacts of blood glucose and DM on ILT still need to be further explored.