Objective: To investigate the risk factors for the occurrence of perioperative complications in patients undergoing open surgery for Takayasu arteritis (TA).
Methods: The data of the 136 TA patients undergoing open revascularization from January 2003 to December 2018 were retrospectively analyzed and the risk factors for perioperative complications of open surgery were determined by univariate and multivariate statistical tests. 
Results: In the 136 patients, open operation was performed 141 times, involving 257 lesions. Thirty-six episodes (25.5%) of perioperative complications occurred in the patients, including death in 5 patients (3.7%). The results of univariate analysis showed that the history of cerebral infarction, preoperative increased CRP level, carotid artery involvement, perioperative blood transfusion, number of involved vessels, artery occlusion time and intraoperative blood loss were associated with the occurrence of perioperative complications (all P<0.05). The results of multivariate Logistic regression analysis showed that the history of cerebral infarction (OR=3.141, 
95% CI=1.062–9.288, P=0.039), number of vascular involvement (OR=1.280, 95% CI=1.016–1.612, P=0.036) and artery occlusion time (OR=1.045, 95% CI=1.007–1.084, P=0.019) were independent risk factors for perioperative complications. tions. 
Conclusion: Preoperative history of cerebral infarction, multiple vascular involvement and prolonged artery occlusion will increase the risk of perioperative complications in TA patients undergoing open surgery.