Abstract:Objective
To study the relation between mammary hyperplasia and expression of VEGF,bFGF.
Methods After the breast mass undergoing core needle biopsy, the pathological type and expression of VEGF and bFGF were observed in 140 cases of breast mass.
Results Of the 140 cases, general hyperplasia was found in 92 cases( 65.7%), atypical hyperplasia in 48 cases(34.3%) . The expression of VEGF and bFGF were increased with the increase of pathological degree of breast hyperplasia (P＜0.05).
Conclusion Angiogenesis is increased with increase of mammary hyperplasia, the more degree of hyperplasia, the more expression of VEGF,bFGF.