Abstract:Objective：To discuss the resection technique for pancreatic carcinoma in patients with tumour invasion to the portal and/or superior mesentery vein, and the clinical significance of palliative resection of pancreatic carcinoma. Methods：The clinical data of 71 cases of pancreatic carcinoma operated on within a period of 3 years were retrospectively reviewed. In patients with tumour invasion to the portal vein, a method of direc transection of pancreas was used in resection of the tumor, and was combined with local radiotherapy and chemotherapy. Results：The resection rate was 57.75%.The complication rate was 22.54%.One patient died of multiple organ failure resulting from pneumonia. The survival rate at 6m,1- and 2-years was 100%,81.69％, and 40.85% respectively. Conclusions：The direct transection method of pancreas resection is a simple and safe method to increase resection rate and prolong survival time for patients with advanced pancreatic carcinoma.